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Peroxisome biogenesis: the peroxisomal endomembrane system and the role of the ER


Peroxisome biogenesis: the peroxisomal endomembrane system and the role of the ER

Titorenko, Vladimir I. and Mullen, Robert T. (2006) Peroxisome biogenesis: the peroxisomal endomembrane system and the role of the ER. The Journal of Cell Biology, 174 (1). pp. 11-17. ISSN 0021-9525

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Official URL: http://dx.doi.org/10.1083/jcb.200604036


Peroxisomes have long been viewed as semiautonomous, static, and homogenous organelles that exist outside the secretory and endocytic pathways of vesicular flow. However, growing evidence supports the view that peroxisomes actually constitute a dynamic endomembrane system that originates from the endoplasmic reticulum. This review highlights the various strategies used by evolutionarily diverse organisms for coordinating the flow of membrane-enclosed carriers through the peroxisomal endomembrane system and critically evaluates the dynamics and molecular mechanisms of this multistep process.

Divisions:Concordia University > Faculty of Arts and Science > Biology
Item Type:Article
Authors:Titorenko, Vladimir I. and Mullen, Robert T.
Journal or Publication:The Journal of Cell Biology
Date:26 June 2006
ID Code:7561
Deposited On:11 May 2011 16:29
Last Modified:11 May 2011 16:29
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