Siegwart, Daniel J. and Oh, Jung Kwon and Matyjaszewski, Krzysztof (2012) ATRP in the design of functional materials for biomedical applications. Progress in Polymer Science, 37 (1). pp. 18-37. ISSN 00796700
DJS-JKO-KM_-_PPS_2011_-_ATRP_Bio_review_Revision_fnal.pdf - Accepted Version
Official URL: http://dx.doi.org/10.1016/j.progpolymsci.2011.08.0...
Atom Transfer Radical Polymerization (ATRP) is an effective technique for the design and preparation of multifunctional, nanostructured materials for a variety of applications in biology and medicine. ATRP enables precise control over macromolecular structure, order, and functionality, which are important considerations for emerging biomedicaldesigns. This article reviews recent advances in the preparation of polymer-based nanomaterials using ATRP, including polymer bioconjugates, block copolymer-based drug delivery systems, cross-linked microgels/nanogels, diagnostic and imaging platforms, tissue engineering hydrogels, and degradable polymers. It is envisioned that precise engineering at the molecular level will translate to tailored macroscopic physical properties, thus enabling control of the key elements for realized biomedicalapplications.
|Divisions:||Concordia University > Faculty of Arts and Science > Chemistry and Biochemistry|
|Authors:||Siegwart, Daniel J. and Oh, Jung Kwon and Matyjaszewski, Krzysztof|
|Journal or Publication:||Progress in Polymer Science|
|Digital Object Identifier (DOI):||10.1016/j.progpolymsci.2011.08.001|
|Deposited By:||ANDREA MURRAY|
|Deposited On:||19 Mar 2012 19:07|
|Last Modified:||05 Nov 2016 01:57|
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