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ATRP in the design of functional materials for biomedical applications

Title:

ATRP in the design of functional materials for biomedical applications

Siegwart, Daniel J. and Oh, Jung Kwon and Matyjaszewski, Krzysztof (2012) ATRP in the design of functional materials for biomedical applications. Progress in Polymer Science, 37 (1). pp. 18-37. ISSN 00796700

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Official URL: http://dx.doi.org/10.1016/j.progpolymsci.2011.08.0...

Abstract

Atom Transfer Radical Polymerization (ATRP) is an effective technique for the design and preparation of multifunctional, nanostructured materials for a variety of applications in biology and medicine. ATRP enables precise control over macromolecular structure, order, and functionality, which are important considerations for emerging biomedicaldesigns. This article reviews recent advances in the preparation of polymer-based nanomaterials using ATRP, including polymer bioconjugates, block copolymer-based drug delivery systems, cross-linked microgels/nanogels, diagnostic and imaging platforms, tissue engineering hydrogels, and degradable polymers. It is envisioned that precise engineering at the molecular level will translate to tailored macroscopic physical properties, thus enabling control of the key elements for realized biomedicalapplications.

Divisions:Concordia University > Faculty of Arts and Science > Chemistry and Biochemistry
Item Type:Article
Refereed:Yes
Authors:Siegwart, Daniel J. and Oh, Jung Kwon and Matyjaszewski, Krzysztof
Journal or Publication:Progress in Polymer Science
Date:2012
ID Code:973679
Deposited By:ANDREA MURRAY
Deposited On:19 Mar 2012 15:07
Last Modified:19 Mar 2012 15:07
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