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Editorial: RNA Regulation in Development and Disease

Title:

Editorial: RNA Regulation in Development and Disease

Chartrand, Pascal, Jaramillo, Maritza and Gamberi, Chiara ORCID: https://orcid.org/0000-0002-7122-6491 (2020) Editorial: RNA Regulation in Development and Disease. Frontiers in Genetics, 11 . ISSN 1664-8021

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Official URL: https://doi.org/10.3389/fgene.2020.00430

Abstract

A wide variety of post-transcriptional regulatory events in the life of an mRNA have emerged as major checkpoints during its temporal and spatial journey within the cell. The advent of deep sequencing technologies combined with various fractionation or enrichment protocols has produced a wealth of data regarding transcripts, their variants and their interactomes. Yet, these data must be integrated with mechanistic and biological frameworks in order to better understand complex and dynamic regulatory networks that tailor mRNA metabolism and shape the cell proteome in healthy and diseased states.

Divisions:Concordia University > Faculty of Arts and Science > Biology
Item Type:Article
Refereed:Yes
Authors:Chartrand, Pascal and Jaramillo, Maritza and Gamberi, Chiara
Journal or Publication:Frontiers in Genetics
Date:2020
Funders:
  • Canadian Institute for Health Research, CIHR, (MOP-130325) and a Fonds de recherche du Québec-Santé, FRQS, Research Chair to PC
  • CIHR (MOP-166017) and Natural Sciences and Engineering Council, NSERC (RGPIN-2019-06671) to MJ;
  • Mathematics of Information Technology and Complex Systems, Mitacs, (IT10214) and a Concordia University CUPFA Professional Development Grant to CG.
Digital Object Identifier (DOI):10.3389/fgene.2020.00430
ID Code:987896
Deposited By: CHIARA GAMBERI
Deposited On:10 Feb 2021 20:23
Last Modified:10 Feb 2021 20:23
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