Allan, B. B., Moyer, B. D., & Balch, W. E. (2000). Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion. Science, 289(5478), 444-448. Alvarez, C., Garcia-Mata, R., Hauri, H. P., & Sztul, E. (2001). The p115-interactive proteins GM130 and giantin participate in endoplasmic reticulum-Golgi traffic. J Biol Chem, 276(4), 2693-2700. doi: 10.1074/jbc.M007957200 Amessou, M., A. Fradagrada, T. Falguieres, J.M. Lord, D.C. Smith, L.M. Roberts, C. Lamaze, and L. Johannes (2007). Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins. J Cell Sci, 120(Pt 8), 1457-1468. doi: 10.1242/jcs.03436 Appenzeller-Herzog, C., & Hauri, H. P. (2006). The ER-Golgi intermediate compartment (ERGIC): in search of its identity and function. J Cell Sci, 119(Pt 11), 2173-2183. doi: 10.1242/jcs.03019 Aridor, M., Bannykh, S. I., Rowe, T., & Balch, W. E. (1995). Sequential coupling between COPII and COPI vesicle coats in endoplasmic reticulum to Golgi transport. J Cell Biol, 131(4), 875-893. Aridor, M., & Hannan, L. A. (2000). Traffic jam: a compendium of human diseases that affect intracellular transport processes. Traffic, 1(11), 836-851. Aridor, M., & Hannan, L. A. (2002). Traffic jams II: an update of diseases of intracellular transport. Traffic, 3(11), 781-790. Baba, M., Osumi, M., Scott, S. V., Klionsky, D. J., & Ohsumi, Y. (1997). Two distinct pathways for targeting proteins from the cytoplasm to the vacuole/lysosome. J Cell Biol, 139(7), 1687-1695. Bachinger, H. P., Doege, K. J., Petschek, J. P., Fessler, L. I., & Fessler, J. H. (1982). Structural implications from an electronmicroscopic comparison of procollagen V with procollagen I, pC-collagen I, procollagen IV, and a Drosophila procollagen. J Biol Chem, 257(24), 14590-14592. Bacon, R. A., Salminen, A., Ruohola, H., Novick, P., & Ferro-Novick, S. (1989). The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants. J Cell Biol, 109(3), 1015-1022. Balch, W. E., Dunphy, W. G., Braell, W. A., & Rothman, J. E. (1984). Reconstitution of the transport of protein between successive compartments of the Golgi measured by the coupled incorporation of N-acetylglucosamine. Cell, 39(2 Pt 1), 405-416. Barlowe, C., L. Orci, T. Yeung, M. Hosobuchi, S. Hamamoto, N. Salama, M.F. Rexach, M. Ravazzola, M. Amherdt, and R. Schekman. (1994). COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell, 77(6), 895-907. Barrowman, J., Sacher, M., & Ferro-Novick, S. (2000). TRAPP stably associates with the Golgi and is required for vesicle docking. EMBO J, 19(5), 862-869. doi: 10.1093/emboj/19.5.862 Bassik, M.C., M. Kampmann, R.J. Lebbink, S. Wang, M.Y. Hein, I. Poser, J. Weibezahn, M.A. Horlbeck, S. Chen, M. Mann, A.A. Hyman, E.M. Leproust, M.T. McManus, and J.S. Weissman. (2013). A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell, 152(4), 909-922. doi: 10.1016/j.cell.2013.01.030 Beard, M., Satoh, A., Shorter, J., & Warren, G. (2005). A cryptic Rab1-binding site in the p115 tethering protein. J Biol Chem, 280(27), 25840-25848. doi: 10.1074/jbc.M503925200 Behrends, C., Sowa, M. E., Gygi, S. P., & Harper, J. W. (2010). Network organization of the human autophagy system. Nature, 466(7302), 68-76. doi: 10.1038/nature09204 Ben-Aroya, S., Coombes, C., Kwok, T., O'Donnell, K. A., Boeke, J. D., & Hieter, P. (2008). Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae. Mol Cell, 30(2), 248-258. doi: 10.1016/j.molcel.2008.02.021 Bentley, M., Liang, Y., Mullen, K., Xu, D., Sztul, E., & Hay, J. C. (2006). SNARE status regulates tether recruitment and function in homotypic COPII vesicle fusion. J Biol Chem, 281(50), 38825-38833. doi: 10.1074/jbc.M606044200 Ben-Ze'ev, A., Robinson, G. S., Bucher, N. L., & Farmer, S. R. (1988). Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes. Proc Natl Acad Sci U S A, 85(7), 2161-2165. Bergmann, J. E., & Singer, S. J. (1983). Immunoelectron microscopic studies of the intracellular transport of the membrane glycoprotein (G) of vesicular stomatitis virus in infected Chinese hamster ovary cells. J Cell Biol, 97(6), 1777-1787. Bielli, A., Haney, C. J., Gabreski, G., Watkins, S. C., Bannykh, S. I., & Aridor, M. (2005). Regulation of Sar1 NH2 terminus by GTP binding and hydrolysis promotes membrane deformation to control COPII vesicle fission. J Cell Biol, 171(6), 919-924. doi: 10.1083/jcb.200509095 Blower, M. D., Feric, E., Weis, K., & Heald, R. (2007). Genome-wide analysis demonstrates conserved localization of messenger RNAs to mitotic microtubules. J Cell Biol, 179(7), 1365-1373. doi: 10.1083/jcb.200705163 Bogershausen, N., N. Shahrzad, J.X. Chong, J.C. von Kleist-Retzow, D. Stanga, Y. Li, F.P. Bernier, C.M. Loucks, R. Wirth, E.G. Puffenberger, R.A. Hegele, J. Schreml, G. Lapointe, K. Keupp, C.L. Brett, R. Anderson, A. Hahn, A.M. Innes, O. Suchowersky, M.B. Mets, G. Nurnberg, D.R. McLeod, H. Thiele, D. Waggoner, J. Altmuller, K.M. Boycott, B. Schoser, P. Nurnberg, C. Ober, R. Heller, J.S. Parboosingh, B. Wollnik, M. Sacher, and R.E. Lamont. (2013). Recessive TRAPPC11 Mutations Cause a Disease Spectrum of Limb Girdle Muscular Dystrophy and Myopathy with Movement Disorder and Intellectual Disability. Am J Hum Genet, 93(1), 181-190. doi: 10.1016/j.ajhg.2013.05.028 Bonifacino, J. S., & Glick, B. S. (2004). The mechanisms of vesicle budding and fusion. Cell, 116(2), 153-166. Bonifacino, J. S., & Lippincott-Schwartz, J. (2003). Coat proteins: shaping membrane transport. Nat Rev Mol Cell Biol, 4(5), 409-414. doi: 10.1038/nrm1099 Boycott, K.M., J.S. Parboosingh, B.N. Chodirker, R.B. Lowry, D.R. McLeod, J. Morris, C.R. Greenberg, A.E. Chudley, F.P. Bernier, J. Midgley, L.B. Moller, and A.M. Innes. (2008). Clinical genetics and the Hutterite population: a review of Mendelian disorders. Am J Med Genet A, 146A(8), 1088-1098. doi: 10.1002/ajmg.a.32245 Boyd, C., Hughes, T., Pypaert, M., & Novick, P. (2004). Vesicles carry most exocyst subunits to exocytic sites marked by the remaining two subunits, Sec3p and Exo70p. J Cell Biol, 167(5), 889-901. doi: 10.1083/jcb.200408124 Brandon, E., Szul, T., Alvarez, C., Grabski, R., Benjamin, R., Kawai, R., & Sztul, E. (2006). On and off membrane dynamics of the endoplasmic reticulum-golgi tethering factor p115 in vivo. Mol Biol Cell, 17(7), 2996-3008. doi: 10.1091/mbc.E05-09-0862 Brunet, S., B. Noueihed, N. Shahrzad, D. Saint-Dic, B. Hasaj, T.L. Guan, A. Moores, C. Barlowe, and M. Sacher. (2012). The SMS domain of Trs23p is responsible for the in vitro appearance of the TRAPP I complex in Saccharomyces cerevisiae. Cell Logist, 2(1), 28-42. doi: 10.4161/cl.19414 Brunet, S., Shahrzad, N., Saint-Dic, D., Dutczak, H., & Sacher, M. (2013). A trs20 Mutation That Mimics an SEDT-Causing Mutation Blocks Selective and Non-Selective Autophagy: A Model for TRAPP III Organization. Traffic. doi: 10.1111/tra.12095 Cai, H., Reinisch, K., & Ferro-Novick, S. (2007a). Coats, tethers, Rabs, and SNAREs work together to mediate the intracellular destination of a transport vesicle. Dev Cell, 12(5), 671-682. doi: 10.1016/j.devcel.2007.04.005 Cai, H., S. Yu, S. Menon, Y. Cai, D. Lazarova, C. Fu, K. Reinisch, J.C. Hay, and S. Ferro-Novick. (2007b). TRAPPI tethers COPII vesicles by binding the coat subunit Sec23. Nature, 445(7130), 941-944. doi: 10.1038/nature05527 Cai, H., Zhang, Y., Pypaert, M., Walker, L., & Ferro-Novick, S. (2005). Mutants in trs120 disrupt traffic from the early endosome to the late Golgi. J Cell Biol, 171(5), 823-833. doi: 10.1083/jcb.200505145 Cai, Y., H.F. Chin, D. Lazarova, S. Menon, C. Fu, H. Cai, A. Sclafani, D.W. Rodgers, E.M. De La Cruz, S. Ferro-Novick, and K.M. Reinisch. (2008). The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes. Cell, 133(7), 1202-1213. doi: 10.1016/j.cell.2008.04.049 Cao, X., Ballew, N., & Barlowe, C. (1998). Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins. EMBO J, 17(8), 2156-2165. doi: 10.1093/emboj/17.8.2156 Cao, Y., Cheong, H., Song, H., & Klionsky, D. J. (2008). In vivo reconstitution of autophagy in Saccharomyces cerevisiae. J Cell Biol, 182(4), 703-713. doi: 10.1083/jcb.200801035 Caro, L. G., & Palade, G. E. (1964). Protein Synthesis, Storage, and Discharge in the Pancreatic Exocrine Cell. An Autoradiographic Study. J Cell Biol, 20, 473-495. Carr, C. M., Grote, E., Munson, M., Hughson, F. M., & Novick, P. J. (1999). Sec1p binds to SNARE complexes and concentrates at sites of secretion. J Cell Biol, 146(2), 333-344. Chen, S., Cai, H., Park, S. K., Menon, S., Jackson, C. L., & Ferro-Novick, S. (2011). Trs65p, a subunit of the Ypt1p GEF TRAPPII, interacts with the Arf1p exchange factor Gea2p to facilitate COPI-mediated vesicle traffic. Mol Biol Cell, 22(19), 3634-3644. doi: 10.1091/mbc.E11-03-0197 Cheong, H., & Klionsky, D. J. (2008). Dual role of Atg1 in regulation of autophagy-specific PAS assembly in Saccharomyces cerevisiae. Autophagy, 4(5), 724-726. Cheong, H., Yorimitsu, T., Reggiori, F., Legakis, J. E., Wang, C. W., & Klionsky, D. J. (2005). Atg17 regulates the magnitude of the autophagic response. Mol Biol Cell, 16(7), 3438-3453. doi: 10.1091/mbc.E04-10-0894 Chiari, R., Foury, F., De Plaen, E., Baurain, J. F., Thonnard, J., & Coulie, P. G. (1999). Two antigens recognized by autologous cytolytic T lymphocytes on a melanoma result from a single point mutation in an essential housekeeping gene. Cancer Res, 59(22), 5785-5792. Choi, C., Davey, M., Schluter, C., Pandher, P., Fang, Y., Foster, L. J., & Conibear, E. (2011). Organization and assembly of the TRAPPII complex. Traffic, 12(6), 715-725. doi: 10.1111/j.1600-0854.2011.01181.x Choi, M. Y., Chan, C. C., Chan, D., Luk, K. D., Cheah, K. S., & Tanner, J. A. (2009). Biochemical consequences of sedlin mutations that cause spondyloepiphyseal dysplasia tarda. Biochem J, 423(2), 233-242. doi: 10.1042/BJ20090541 Choi, W. I., Qama, D., Lee, M. Y., & Kwon, K. Y. (2013). Pleural cancer antigen-125 levels in benign and malignant pleural effusions. Int J Tuberc Lung Dis, 17(5), 693-697. doi: 10.5588/ijtld.12.0635 Clary, D. O., & Rothman, J. E. (1990). Purification of three related peripheral membrane proteins needed for vesicular transport. J Biol Chem, 265(17), 10109-10117. Conibear, E. (2011). Vesicle transport: springing the TRAPP. Curr Biol, 21(13), R506-508. doi: 10.1016/j.cub.2011.05.045 Cox, R., Chen, S. H., Yoo, E., & Segev, N. (2007). Conservation of the TRAPPII-specific subunits of a Ypt/Rab exchanger complex. BMC Evol Biol, 7, 12. doi: 10.1186/1471-2148-7-12 Cuervo, A. M. (2004). Autophagy: many paths to the same end. Mol Cell Biochem, 263(1-2), 55-72. de Ligt, J., M.H. Willemsen, B.W. van Bon, T. Kleefstra, H.G. Yntema, T. Kroes, A.T. Vulto-van Silfhout, D.A. Koolen, P. de Vries, C. Gilissen, M. del Rosario, A. Hoischen, H. Scheffer, B.B. de Vries, H.G. Brunner, J.A. Veltman, and L.E. Vissers. (2012). Diagnostic exome sequencing in persons with severe intellectual disability. N Engl J Med, 367(20), 1921-1929. doi: 10.1056/NEJMoa1206524 Dulubova, I., Sugita, S., Hill, S., Hosaka, M., Fernandez, I., Sudhof, T. C., & Rizo, J. (1999). A conformational switch in syntaxin during exocytosis: role of munc18. EMBO J, 18(16), 4372-4382. doi: 10.1093/emboj/18.16.4372 Duncan, J. R., & Kornfeld, S. (1988). Intracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatus. J Cell Biol, 106(3), 617-628. Fukuda, M., Viitala, J., Matteson, J., & Carlsson, S. R. (1988). Cloning of cDNAs encoding human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Comparison of their deduced amino acid sequences. J Biol Chem, 263(35), 18920-18928. Ganley, I. G., Carroll, K., Bittova, L., & Pfeffer, S. (2004). Rab9 GTPase regulates late endosome size and requires effector interaction for its stability. Mol Biol Cell, 15(12), 5420-5430. doi: 10.1091/mbc.E04-08-0747 Garcia, I. A., Martinez, H. E., & Alvarez, C. (2011). Rab1b regulates COPI and COPII dynamics in mammalian cells. Cell Logist, 1(4), 159-163. doi: 10.4161/cl.1.4.18221 Gavin, A.C., M. Bosche, R. Krause, P. Grandi, M. Marzioch, A. Bauer, J. Schultz, J.M. Rick, A.M. Michon, C.M. Cruciat, M. Remor, C. Hofert, M. Schelder, M. Brajenovic, H. Ruffner, A. Merino, K. Klein, M. Hudak, D. Dickson, T. Rudi, V. Gnau, A. Bauch, S. Bastuck, B. Huhse, C. Leutwein, M.A. Heurtier, R.R. Copley, A. Edelmann, E. Querfurth, V. Rybin, G. Drewes, M. Raida, T. Bouwmeester, P. Bork, B. Seraphin, B. Kuster, G. Neubauer, and G. Superti-Furga. (2002). Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature, 415(6868), 141-147. doi: 10.1038/415141a Gecz, J., Hillman, M. A., Gedeon, A. K., Cox, T. C., Baker, E., & Mulley, J. C. (2000). Gene structure and expression study of the SEDL gene for spondyloepiphyseal dysplasia tarda. Genomics, 69(2), 242-251. doi: 10.1006/geno.2000.6326 Gecz, J., Shaw, M. A., Bellon, J. R., & de Barros Lopes, M. (2003). Human wild-type SEDL protein functionally complements yeast Trs20p but some naturally occurring SEDL mutants do not. Gene, 320, 137-144. Gedeon, A.K., A. Colley, R. Jamieson, E.M. Thompson, J. Rogers, D. Sillence, G.E. Tiller, J.C. Mulley, and J. Gecz. (1999). Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda. Nat Genet, 22(4), 400-404. doi: 10.1038/11976 Gedeon, A.K., G.E. Tiller, M. Le Merrer, S. Heuertz, L. Tranebjaerg, D. Chitayat, S. Robertson, I.A. Glass, R. Savarirayan, W.G. Cole, D.L. Rimoin, B.G. Kousseff, H. Ohashi, B. Zabel, A. Munnich, J. Gecz, and J.C. Mulley. (2001). The molecular basis of X-linked spondyloepiphyseal dysplasia tarda. Am J Hum Genet, 68(6), 1386-1397. doi: 10.1086/320592 Ghosh, A. K., Majumder, M., Steele, R., White, R. A., & Ray, R. B. (2001). A novel 16-kilodalton cellular protein physically interacts with and antagonizes the functional activity of c-myc promoter-binding protein 1. Mol Cell Biol, 21(2), 655-662. doi: 10.1128/MCB.21.2.655-662.2001 Ghosh, A. K., Steele, R., & Ray, R. B. (2003). Modulation of human luteinizing hormone beta gene transcription by MIP-2A. J Biol Chem, 278(26), 24033-24038. doi: 10.1074/jbc.M211982200 Gillingham, A. K., & Munro, S. (2003). Long coiled-coil proteins and membrane traffic. Biochim Biophys Acta, 1641(2-3), 71-85. Gonzalez, L. C., Jr., Weis, W. I., & Scheller, R. H. (2001). A novel snare N-terminal domain revealed by the crystal structure of Sec22b. J Biol Chem, 276(26), 24203-24211. doi: 10.1074/jbc.M101584200 Grabski, R., Z. Balklava, P. Wyrozumska, T. Szul, E. Brandon, C. Alvarez, Z.G. Holloway, and E. Sztul. (2012a). Identification of a functional domain within the p115 tethering factor that is required for Golgi ribbon assembly and membrane trafficking. J Cell Sci, 125(Pt 8), 1896-1909. doi: 10.1242/jcs.090571 Grabski, R., Hay, J., & Sztul, E. (2012b). Tethering factor P115: A new model for tether-SNARE interactions. Bioarchitecture, 2(5). Gross, J.M., B.D. Perkins, A. Amsterdam, A. Egana, T. Darland, J.I. Matsui, S. Sciascia, N. Hopkins, and J.E. Dowling. (2005). Identification of zebrafish insertional mutants with defects in visual system development and function. Genetics, 170(1), 245-261. doi: 10.1534/genetics.104.039727 Gwynn, B., Smith, R. S., Rowe, L. B., Taylor, B. A., & Peters, L. L. (2006). A mouse TRAPP-related protein is involved in pigmentation. Genomics, 88(2), 196-203. doi: 10.1016/j.ygeno.2006.04.002 Hirschberg, K., Miller, C. M., Ellenberg, J., Presley, J. F., Siggia, E. D., Phair, R. D., & Lippincott-Schwartz, J. (1998). Kinetic analysis of secretory protein traffic and characterization of golgi to plasma membrane transport intermediates in living cells. J Cell Biol, 143(6), 1485-1503. Hostetler, J. A. (1985). History and relevance of the Hutterite population for genetic studies. Am J Med Genet, 22(3), 453-462. doi: 10.1002/ajmg.1320220303 Hou, H., K. Subramanian, T.J. LaGrassa, D. Markgraf