This article provides an overview of the application of computational fluid dynamics (CFD) in building performance simulation for the outdoor environment, focused on four topics: (1) pedestrian wind environment around buildings, (2) wind-driven rain on building facades, (3) convective heat transfer coefficients at exterior building surfaces and (4) air pollutant dispersion around buildings. For each topic, its background, the need for CFD, an overview of some past CFD studies, a discussion about accuracy and some perspectives for practical application are provided. This article indicates that for all four topics, CFD offers considerable advantages compared with wind tunnel modelling or (semi-)empirical formulae because it can provide detailed whole-flow field data under fully controlled conditions and without similarity constraints. The main limitations are the deficiencies of steady Reynolds-averaged Navier–Stokes modelling, the increased complexity and computational expense of large eddy simulation and the requirement of systematic and time-consuming CFD solution verification and validation studies.