1. Karatsoreos IN. Links between Circadian Rhythms and Psychiatric Disease. Front Behav Neurosci. 2014;8:162. pmid:24834040 2. Lamont EW, Legault-Coutu D, Cermakian N, Boivin DB. The role of circadian clock genes in mental disorders. Dialogues Clin Neurosci. 2007;9(3):333–42. pmid:17969870 3. Szelenberger W, Soldatos C. Sleep disorders in psychiatric practice. World Psychiatry. 2005;4(3):186–90. pmid:16633547 4. Berle JO, Hauge ER, Oedegaard KJ, Holsten F, Fasmer OB. Actigraphic registration of motor activity reveals a more structured behavioural pattern in schizophrenia than in major depression. BMC Res Notes. 2010;3:149. pmid:20507606 5. Jones SG, Benca RM. Circadian Disruption in Psychiatric Disorders. Sleep Med Clin. 2015;10(4):481–93. pmid:26568124 6. Dardente H, Cermakian N. Molecular circadian rhythms in central and peripheral clocks in mammals. Chronobiol Int. 2007;24(2):195–213. pmid:17453843 7. Kalsbeek A, Palm IF, La Fleur SE, Scheer FA, Perreau-Lenz S, Ruiter M, et al. SCN outputs and the hypothalamic balance of life. J Biol Rhythms. 2006;21(6):458–69. pmid:17107936 8. Kripke DF, Nievergelt CM, Joo E, Shekhtman T, Kelsoe JR. Circadian polymorphisms associated with affective disorders. J Circadian Rhythms. 2009;7:2. pmid:19166596 9. Nievergelt CM, Kripke DF, Barrett TB, Burg E, Remick RA, Sadovnick AD, et al. Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2006;141B(3):234–41. pmid:16528748 10. Patel SD, Le-Niculescu H, Koller DL, Green SD, Lahiri DK, McMahon FJ, et al. Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics. Am J Med Genet B Neuropsychiatr Genet. 2010;153B(4):850–77. pmid:20468069 11. Pickard BS, Christoforou A, Thomson PA, Fawkes A, Evans KL, Morris SW, et al. Interacting haplotypes at the NPAS3 locus alter risk of schizophrenia and bipolar disorder. Mol Psychiatry. 2009;14(9):874–84. pmid:18317462 12. Soria V, Martinez-Amoros E, Escaramis G, Valero J, Perez-Egea R, Garcia C, et al. Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder. Neuropsychopharmacology. 2010;35(6):1279–89. pmid:20072116 13. Cryan JF, Markou A, Lucki I. Assessing antidepressant activity in rodents: recent developments and future needs. Trends Pharmacol Sci. 2002;23(5):238–45. pmid:12008002 14. Gronli J, Murison R, Fiske E, Bjorvatn B, Sorensen E, Portas CM, et al. Effects of chronic mild stress on sexual behavior, locomotor activity and consumption of sucrose and saccharine solutions. Physiol Behav. 2005;84(4):571–7. pmid:15811392 15. Jiang WG, Li SX, Zhou SJ, Sun Y, Shi J, Lu L. Chronic unpredictable stress induces a reversible change of PER2 rhythm in the suprachiasmatic nucleus. Brain Res. 2011;1399:25–32. pmid:21621196 16. Logan RW, Edgar N, Gillman AG, Hoffman D, Zhu X, McClung CA. Chronic Stress Induces Brain Region-Specific Alterations of Molecular Rhythms that Correlate with Depression-like Behavior in Mice. Biol Psychiatry. 2015;78(4):249–58. pmid:25771506 17. Griesauer I, Diao W, Ronovsky M, Elbau I, Sartori S, Singewald N, et al. Circadian abnormalities in a mouse model of high trait anxiety and depression. Ann Med. 2014;46(3):148–54. pmid:24405329 18. Schaufler J, Ronovsky M, Savalli G, Cabatic M, Sartori SB, Singewald N, et al. Fluoxetine normalizes disrupted light-induced entrainment, fragmented ultradian rhythms and altered hippocampal clock gene expression in an animal model of high trait anxiety- and depression-related behavior. Ann Med. 2016;48(1–2):17–27. pmid:26679264 19. Landgraf D, Long JE, Proulx CD, Barandas R, Malinow R, Welsh DK. Genetic Disruption of Circadian Rhythms in the Suprachiasmatic Nucleus Causes Helplessness, Behavioral Despair, and Anxiety-like Behavior in Mice. Biol Psychiatry. 2016. 20. Jones N, King SM. Influence of circadian phase and test illumination on pre-clinical models of anxiety. Physiol Behav. 2001;72(1–2):99–106. pmid:11239986 21. Carobrez AP, Bertoglio LJ. Ethological and temporal analyses of anxiety-like behavior: the elevated plus-maze model 20 years on. Neurosci Biobehav Rev. 2005;29(8):1193–205. pmid:16084592 22. Sestakova N, Puzserova A, Kluknavsky M, Bernatova I. Determination of motor activity and anxiety-related behaviour in rodents: methodological aspects and role of nitric oxide. Interdiscip Toxicol. 2013;6(3):126–35. pmid:24678249 23. Porsolt RD, Brossard G, Hautbois C, Roux S. Rodent models of depression: forced swimming and tail suspension behavioral despair tests in rats and mice. Curr Protoc Neurosci. 2001;Chapter 8:Unit 8 10A. pmid:18428536 24. Kelliher P, Connor TJ, Harkin A, Sanchez C, Kelly JP, Leonard BE. Varying responses to the rat forced-swim test under diurnal and nocturnal conditions. Physiol Behav. 2000;69(4–5):531–9. pmid:10913793 25. Welsh DK, Engel EM, Richardson GS, Dement WC. Precision of circadian wake and activity onset timing in the mouse. J Comp Physiol A. 1986;158(6):827–34. pmid:3735167 26. McClung CA. Circadian genes, rhythms and the biology of mood disorders. Pharmacol Ther. 2007;114(2):222–32. pmid:17395264 27. Spencer S, Falcon E, Kumar J, Krishnan V, Mukherjee S, Birnbaum SG, et al. Circadian genes Period 1 and Period 2 in the nucleus accumbens regulate anxiety-related behavior. Eur J Neurosci. 2013;37(2):242–50. pmid:23039899 28. Stevens RG, Blask DE, Brainard GC, Hansen J, Lockley SW, Provencio I, et al. Meeting report: the role of environmental lighting and circadian disruption in cancer and other diseases. Environ Health Perspect. 2007;115(9):1357–62. pmid:17805428 29. Harbour VL, Weigl Y, Robinson B, Amir S. Comprehensive mapping of regional expression of the clock protein PERIOD2 in rat forebrain across the 24-h day. PLoS One. 2013;8(10):e76391. pmid:24124556 30. Dhabhar FS, McEwen BS, Spencer RL. Adaptation to prolonged or repeated stress—comparison between rat strains showing intrinsic differences in reactivity to acute stress. Neuroendocrinology. 1997;65(5):360–8. pmid:9158068 31. Goswami S, Cascardi M, Rodriguez-Sierra OE, Duvarci S, Pare D. Impact of predatory threat on fear extinction in Lewis rats. Learn Mem. 2010;17(10):494–501. pmid:20929713 32. Hinojosa FR, Spricigo L Jr., Izidio GS, Bruske GR, Lopes DM, Ramos A. Evaluation of two genetic animal models in behavioral tests of anxiety and depression. Behav Brain Res. 2006;168(1):127–36. pmid:16324754 33. Ramos A, Kangerski AL, Basso PF, Da Silva Santos JE, Assreuy J, Vendruscolo LF, et al. Evaluation of Lewis and SHR rat strains as a genetic model for the study of anxiety and pain. Behav Brain Res. 2002;129(1–2):113–23. pmid:11809502 34. Molendijk ML, de Kloet ER. Immobility in the forced swim test is adaptive and does not reflect depression. Psychoneuroendocrinology. 2015;62:389–91. pmid:26386543 35. Nishimura H, Tsuda A, Oguchi M, Ida Y, Tanaka M. Is immobility of rats in the forced swim test "behavioral despair"? Physiol Behav. 1988;42(1):93–5. pmid:3387484 36. Aschoff J, Daan S, Figala J, Muller K. Precision of entrained circadian activity rhythms under natural photoperiodic conditions. Naturwissenschaften. 1972;59(6):276–7. pmid:5050763 37. Evans JA, Leise TL, Castanon-Cervantes O, Davidson AJ. Neural correlates of individual differences in circadian behaviour. Proc Biol Sci. 2015;282(1810). 38. Martynhak BJ, Pereira M, de Souza CP, Andreatini R. Stretch, Shrink, and Shatter the Rhythms: The Intrinsic Circadian Period in Mania and Depression. CNS Neurol Disord Drug Targets. 2015;14(8):963–9. pmid:26350335 39. LeGates TA, Altimus CM, Wang H, Lee HK, Yang S, Zhao H, et al. Aberrant light directly impairs mood and learning through melanopsin-expressing neurons. Nature. 2012;491(7425):594–8. pmid:23151476 40. Wirz-Justice A, Benedetti F, Berger M, Lam RW, Martiny K, Terman M, et al. Chronotherapeutics (light and wake therapy) in affective disorders. Psychol Med. 2005;35(7):939–44. pmid:16045060 41. Lewy AJ, Lefler BJ, Emens JS, Bauer VK. The circadian basis of winter depression. Proc Natl Acad Sci U S A. 2006;103(19):7414–9. pmid:16648247 42. Wirz-Justice A, Graw P, Krauchi K, Gisin B, Jochum A, Arendt J, et al. Light therapy in seasonal affective disorder is independent of time of day or circadian phase. Arch Gen Psychiatry. 1993;50(12):929–37. pmid:8250678 43. Duffy JF, Kronauer RE, Czeisler CA. Phase-shifting human circadian rhythms: influence of sleep timing, social contact and light exposure. J Physiol. 1996;495 (Pt 1):289–97. 44. Monk TH, Petrie SR, Hayes AJ, Kupfer DJ. Regularity of daily life in relation to personality, age, gender, sleep quality and circadian rhythms. J Sleep Res. 1994;3(4):196–205. pmid:10607126 45. Mrosovsky N. Phase response curves for social entrainment. J Comp Physiol A. 1988;162(1):35–46. pmid:3351785 46. Valentinuzzi VS, Scarbrough K, Takahashi JS, Turek FW. Effects of aging on the circadian rhythm of wheel-running activity in C57BL/6 mice. Am J Physiol. 1997;273(6 Pt 2):R1957–64. pmid:9435649