This research uncovers the potential benefits of textile interventions with older male cancer patients in waiting spaces, supporting clients through their trajectory of treatment. This theoretical inquiry asks the following questions: “How can art therapy enhance healing within a hospital setting for older men receiving cancer treatment?” and “How could textile-based art therapy interventions, such as knitting, be used during cancer treatment?” A review and synthesis of related literature found that older male cancer patients are at risk for loneliness and social isolation, yet are faced with many barriers to receive social programming. Textile interventions – and knitting specifically – are suggested as a means of increasing sense of inclusion, distracting from symptoms associated with cancer treatment, and providing an opportunity for creativity in clinical and other waiting spaces. The text builds a theoretical foundation from which new frameworks for treatment of this population could be developed.