Login | Register

The effects of intranasal oxytocin administration on resting state electroencephalography frontal asymmetry

Title:

The effects of intranasal oxytocin administration on resting state electroencephalography frontal asymmetry

Orlando, Mark Anthony (2015) The effects of intranasal oxytocin administration on resting state electroencephalography frontal asymmetry. Masters thesis, Concordia University.

This is the latest version of this item.

[img]
Preview
Text (application/pdf)
Orlando_MA_F2015.pdf - Accepted Version
592kB

Abstract

Research suggests that the nonapeptide oxytocin plays an important role in social functioning, and that the intranasal administration of exogenous oxytocin promotes prosocial behaviours. The mechanisms underlying oxytocin’s effects on social cognition and behaviour are not yet well understood. One viable hypothesis is that oxytocin acts upon frontal asymmetry. Relative left frontal neural activation has been consistently associated with approach behaviours and shares a number of other similarities with intranasal oxytocin administration. For the first time, we examined the hypothesis that oxytocin increases relative left frontal neural activation using electroencephalography methodology. In a double-blind within-subject experiment, 48 participants self-administered a 24 I.U. dose of intranasal oxytocin and placebo approximately one week apart. Following drug administration, alpha band power was recorded at frontal and parietal sites during eight 60 second trials. Intranasal oxytocin administration did not produce any significant changes in frontal asymmetry (F(1, 47) = .273, p= .604, partial η2 = .006). This relation did not interact with sex nor measures of depression, which have been shown to moderate the effects of intranasal oxytocin in prior investigations. Oxytocin administration does not appear to increase relative left frontal neural activation. Additional considerations and interpretations are discussed.

Divisions:Concordia University > Faculty of Arts and Science > Psychology
Item Type:Thesis (Masters)
Authors:Orlando, Mark Anthony
Institution:Concordia University
Degree Name:M.A.
Program:Psychology
Date:September 2015
Thesis Supervisor(s):Ellenbogen, Mark
ID Code:980614
Deposited By: Mark Anthony Orlando
Deposited On:29 Oct 2015 15:17
Last Modified:18 Jan 2018 17:51

Available Versions of this Item

  • The effects of intranasal oxytocin administration on resting state electroencephalography frontal asymmetry. (deposited 29 Oct 2015 15:17) [Currently Displayed]
All items in Spectrum are protected by copyright, with all rights reserved. The use of items is governed by Spectrum's terms of access.

Repository Staff Only: item control page

Downloads per month over past year

Back to top Back to top