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Non-muscle Myosin Contractility in the Neuroblasts Influences Epidermal Morphogenesis

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Non-muscle Myosin Contractility in the Neuroblasts Influences Epidermal Morphogenesis

Mastronardi, Karina (2016) Non-muscle Myosin Contractility in the Neuroblasts Influences Epidermal Morphogenesis. Masters thesis, Concordia University.

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Abstract

Tissue morphogenesis requires myosin-dependent events such as cell shape changes and migration to be coordinated between cells within a tissue, and/or with cells from other tissues. However, few studies have investigated the simultaneous morphogenesis of multiple tissues in vivo. We found that during C. elegans ventral enclosure, when epidermal cells collectively migrate to cover the ventral surface of the embryo, the underlying neuroblasts (neuronal precursor cells) also undergo morphogenesis. We found that myosin accumulates as foci along the junction-free edges of the ventral epidermal cells to form a ring, whose closure is myosin- dependent. We also observed the accumulation of myosin foci and the adhesion junction protein

Divisions:Concordia University > Faculty of Arts and Science > Biology
Item Type:Thesis (Masters)
Authors:Mastronardi, Karina
Institution:Concordia University
Degree Name:M. Sc.
Program:Biology
Date:5 January 2016
Thesis Supervisor(s):Piekny, Alisa
ID Code:980784
Deposited By: KARINA MASTRONARDI
Deposited On:16 Jun 2016 14:57
Last Modified:18 Jan 2018 17:52
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