Login | Register

Dopamine Signaling Is Critical for Supporting Cue-Driven Behavioral Control


Dopamine Signaling Is Critical for Supporting Cue-Driven Behavioral Control

Iordanova, Mihaela D. (2019) Dopamine Signaling Is Critical for Supporting Cue-Driven Behavioral Control. Neuroscience . ISSN 03064522 (In Press)

[thumbnail of In press, Accepted manuscript]
Text (In press, Accepted manuscript) (application/pdf)
Dopamine-Signaling-Is-Critical-for-Supporting-Cue-Driven-Beha_2019_Neuroscie.pdf - Accepted Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Official URL: http://dx.doi.org/10.1016/j.neuroscience.2019.05.0...


Mesolimbic dopamine has been implicated in reward learning. Fischbach-Weiss and Janak (this issue) use optogenetics to attenuate dopamine signaling and study its role in cue-driven motivated behaviour.

Divisions:Concordia University > Faculty of Arts and Science > Psychology
Item Type:Article
Authors:Iordanova, Mihaela D.
Journal or Publication:Neuroscience
Date:28 April 2019
Digital Object Identifier (DOI):10.1016/j.neuroscience.2019.05.002
Keywords:learning; memory; action; mesolimbic dopamine; reward
ID Code:985441
Deposited By: Monique Lane
Deposited On:03 Jun 2019 18:24
Last Modified:03 May 2020 00:00


KC Berridge The debate over dopamine's role in reward: the case for incentive salience Psychopharmacology (Berl), 191 (2007), pp. 391-431

CY Chang, GR Esber, Y Marrero-Garcia, H-J Yau, A Bonci, G Schoenbaum Brief optogenetic inhibition of dopamine neurons mimics endogenous negative reward prediction errors Nat Neurosci, 19 (2016), pp. 111-116

CY Chang, M Gardner, MG Di Tillio, G Schoenbaum Optogenetic blockade of dopamine transients prevents learning induced by changes in reward features Curr Biol, 27 (2017), pp. 3480-3486.e3483

A Dickinson, J Smith, J Mirenowicz Dissociation of Pavlovian and instrumental incentive learning under dopamine antagonists
Behav Neurosci, 114 (2000), pp. 468-483

KB Franklin, SN McCoy Pimozide-induced extinction in rats: stimulus control of responding rules out motor deficit Pharmacol Biochem Behav, 11 (1979), pp. 71-75

S Fischbach-Weiss, PH Janak Decreases in cued reward seeking after reward-paired inhibition of mesolimbic dopamine Neuroscience (2019)

AA Hamid, JR Pettibone, OS Mabrouk, VL Hetrick, R Schmidt, CM Vander Weele, RT Kennedy, BJ Aragona, JD Berke Mesolimbic dopamine signals the value of work Nat Neurosci, 19 (2016), pp. 117-126

Keiflin R, Pribut HJ, Shah NB, Janak PH (2017) Phasic Activation of Ventral Tegmental, but not Substantia Nigra, Dopamine Neurons Promotes Model-Based Pavlovian Reward Learning. bioRxiv:232678.

D Ko, MJ Wanat Phasic dopamine transmission reflects initiation vigor and exerted effort in an action- and region-specific manner
J Neurosci, 36 (2016), pp. 2202-2211

Maes EJ, Sharpe MJ, Gardner MP, Chang CY, Schoenbaum G, Iordanova MD (2019) Causal evidence supporting the proposal that dopamine transients function as a temporal difference prediction error. bioRxiv:520965.

SB Ostlund, KH LeBlanc, AR Kosheleff, KM Wassum, NT Maidment Phasic mesolimbic dopamine signaling encodes the facilitation of incentive motivation produced by repeated cocaine exposure Neuropsychopharmacology, 39 (2014), pp. 2441-2449

RA Rescorla, AR Wagner A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and nonreinforcement
AH Black, WF Prokasy (Eds.), Classical conditioning: II. Current research and theory, Appleton-Century-Crofts, New York (1972), pp. 64-99

W Schultz, P Dayan, PR Montague A neural substrate of prediction and reward Science, 275 (1997), pp. 1593-1599

EE Steinberg, R Keiflin, JR Boivin, IB Witten, K Deisseroth, PH Janak A causal link between prediction errors, dopamine neurons and learning
Nat Neurosci, 16 (2013), pp. 966-973

Sutton RS, Barto AG (1990) Time-derivative models of Pavlovian reinforcement. In M. Gabriel & J. Moore (Eds.), Learning and computational neuroscience: Foundations of adaptive networks (pp. 497–537). Cambridge, MA, US: The MIT Press.

P Waelti, A Dickinson, W Schultzv Dopamine responses comply with basic assumptions of formal learning theory Nature, 412 (2001), pp. 43-48

KM Wassum, SB Ostlund, GC Loewinger, NT Maidment Phasic mesolimbic dopamine release tracks reward seeking during expression of Pavlovian-to-instrumental transfer Biol Psychiatry, 73 (2013), pp. 747-755

RA Wise Dopamine, learning and motivation Nat Rev Neurosci, 5 (2004), pp. 483-494

RA Wise, J Spindler, H deWit, GJ Gerberg Neuroleptic-induced “anhedonia” in rats: pimozide blocks reward quality of food
Science, 201 (1978), pp. 262-264
All items in Spectrum are protected by copyright, with all rights reserved. The use of items is governed by Spectrum's terms of access.

Repository Staff Only: item control page

Downloads per month over past year

Research related to the current document (at the CORE website)
- Research related to the current document (at the CORE website)
Back to top Back to top