Waddington Lamont, Elaine and Renteria Diaz, Laura and Barry Shaw, Jane and Stewart, Jane and Amir, Shimon (2005) Daily restricted feeding rescues a rhythm of period2 expression in the arrhythmic suprachiasmatic nucleus. Neuroscience, 132 (2). pp. 245-248. ISSN 0306-4522
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Official URL: http://dx.doi.org/doi:10.1016/j.neuroscience.2005....
Second only to light, daily restricted feeding schedules can entrain circadian rhythms in mammals [Neurosci Biobehav Rev 4 (1980) 119; J Biol Rhythms 17 (2002) 284]. Contrary to light, however, such feeding schedules have been found not to affect the master circadian clock in the suprachiasmatic nucleus (SCN) [Genes Dev 14 (2000) 2950; Eur J Neurosci 13 (2001) 1190]. Here, we show that in rats that are arrhythmic as a consequence of prolonged housing in constant light, a daily restricted feeding schedule not only restores behavioral rhythmicity, as previously shown [Physiol Behav 53 (1993) 509], but in addition, induces a rhythm of the clock protein, Period2 in the SCN. These findings challenge the idea that the SCN is invulnerable to feeding schedules and call for a reevaluation of the role of the SCN clock in the circadian effects of such schedules.
|Divisions:||Concordia University > Faculty of Arts and Science > Psychology|
|Authors:||Waddington Lamont, Elaine and Renteria Diaz, Laura and Barry Shaw, Jane and Stewart, Jane and Amir, Shimon|
|Journal or Publication:||Neuroscience|
|Deposited By:||SHIMON AMIR|
|Deposited On:||26 Apr 2010 16:22|
|Last Modified:||08 Dec 2010 18:32|
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