Titorenko, Vladimir I. and Rachubinski, Richard A.
The peroxisome: orchestrating important developmental decisions from inside the cell.
The Journal of Cell Biology, 164
- Published Version
Official URL: http://dx.doi.org/10.1083/jcb.200312081
The peroxisome has long been known for its role in lipid metabolism and hydrogen peroxide detoxification. However, growing evidence supports the view that this organelle can also function both as an intracellular signaling compartment and as an organizing platform that orchestrates certain developmental decisions from inside the cell. This review highlights various strategies that peroxisomes employ to regulate the processes of development, differentiation, and morphogenesis and critically evaluates several molecular mechanisms by which peroxisomes promote these processes.
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