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Morphogenesis in Candida albicans*


Morphogenesis in Candida albicans*

Whiteway, Malcolm and Bachewich, Catherine (2007) Morphogenesis in Candida albicans*. Annual Review of Microbiology, 61 (1). pp. 529-553. ISSN 0066-4227

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Official URL: http://dx.doi.org/10.1146/annurev.micro.61.080706....


Candida albicans is termed a dimorphic fungus because it proliferates in either a yeast form or a hyphal form. The switch between these forms is the result of a complex interplay of external and internal factors and is coordinated in part by polarity-regulating proteins that are conserved among eukaryotic cells. However, yeast and hyphal cells are not the only morphological states of C. albicans. The opaque form required for mating, the pseudohyphal cell, and the chlamydospore represent distinct cell types that form in response to specific genetic or environmental conditions. In addition, hyperextended buds can form as a result of various cell cycle–related stresses. Recent studies are beginning to shed light on some of the molecular controls regulating the various morphogenetic forms of this fascinating human pathogen.

Divisions:Concordia University > Faculty of Arts and Science > Biology
Item Type:Article
Authors:Whiteway, Malcolm and Bachewich, Catherine
Journal or Publication:Annual Review of Microbiology
Date:October 2007
ID Code:7580
Deposited On:11 May 2011 21:19
Last Modified:11 May 2011 21:19
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