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Impact of data-dependent model selection on inference

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Impact of data-dependent model selection on inference

Mahmud, Mamun (2000) Impact of data-dependent model selection on inference. Masters thesis, Concordia University.

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Abstract

In this thesis, I consider the problem of accounting for model uncertainty in a parametric regression model with focus on the uncertainty involved in selection of the optimal transformation of a continuous predictor in the Cox proportional hazards model (Cox, 1972). I use the minimum AIC approach to select a posteriori the optimal transformation of a continuous predictor. First, I review literature on criteria and methods for selecting the " best-fitting " model based on the results obtained from a sample, in Chapter 1. Then, in Chapter 2, I discuss the general problem of model selection uncertainty on inference and summarize research in this area. Next, I evaluate the impact of the data-dependent model selection approach on type I error rate through simulations. In simulations, I generate data, assuming both linear and non-linear dependence of hazard on a continuous covariate as well as no association. The generated data are then used to estimate a series of models with various functional form, to assess the impact of model selection on type I error and on statistical power. Some of the above methodological problems are then illustrated in the analysis of a real-life dataset including several cardiovascular risk factors.

Divisions:Concordia University > Faculty of Arts and Science > Mathematics and Statistics
Item Type:Thesis (Masters)
Authors:Mahmud, Mamun
Pagination:xii, 128 leaves ; 29 cm.
Institution:Concordia University
Degree Name:Theses (M.Sc.)
Program:Mathematics and Statistics
Date:2000
ID Code:1158
Deposited By:Concordia University Libraries
Deposited On:27 Aug 2009 13:17
Last Modified:08 Dec 2010 10:18
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