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Daily restricted feeding rescues a rhythm of period2 expression in the arrhythmic suprachiasmatic nucleus

Title:

Daily restricted feeding rescues a rhythm of period2 expression in the arrhythmic suprachiasmatic nucleus

Waddington Lamont, Elaine, Renteria Diaz, Laura, Barry Shaw, Jane, Stewart, Jane and Amir, Shimon (2005) Daily restricted feeding rescues a rhythm of period2 expression in the arrhythmic suprachiasmatic nucleus. Neuroscience, 132 (2). pp. 245-248. ISSN 0306-4522

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Official URL: http://dx.doi.org/doi:10.1016/j.neuroscience.2005....

Abstract

Second only to light, daily restricted feeding schedules can entrain circadian rhythms in mammals [Neurosci Biobehav Rev 4 (1980) 119; J Biol Rhythms 17 (2002) 284]. Contrary to light, however, such feeding schedules have been found not to affect the master circadian clock in the suprachiasmatic nucleus (SCN) [Genes Dev 14 (2000) 2950; Eur J Neurosci 13 (2001) 1190]. Here, we show that in rats that are arrhythmic as a consequence of prolonged housing in constant light, a daily restricted feeding schedule not only restores behavioral rhythmicity, as previously shown [Physiol Behav 53 (1993) 509], but in addition, induces a rhythm of the clock protein, Period2 in the SCN. These findings challenge the idea that the SCN is invulnerable to feeding schedules and call for a reevaluation of the role of the SCN clock in the circadian effects of such schedules.

Divisions:Concordia University > Faculty of Arts and Science > Psychology
Item Type:Article
Refereed:Yes
Authors:Waddington Lamont, Elaine and Renteria Diaz, Laura and Barry Shaw, Jane and Stewart, Jane and Amir, Shimon
Journal or Publication:Neuroscience
Date:2005
Funders:
  • CIHR
  • CURC
Digital Object Identifier (DOI):10.1016/j.neuroscience.2005.01.029
ID Code:6599
Deposited By: SHIMON AMIR
Deposited On:26 Apr 2010 20:22
Last Modified:18 Jan 2018 17:29
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