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Diurnal influences on electrophysiological oscillations and coupling in the dorsal striatum and cerebellar cortex of the anesthetized rat


Diurnal influences on electrophysiological oscillations and coupling in the dorsal striatum and cerebellar cortex of the anesthetized rat

Frederick, Ariana, Bourget-Murray, Jonathan, Chapman, C. Andrew, Amir, Shimon ORCID: https://orcid.org/0000-0003-1919-5023 and Courtemanche, Richard (2014) Diurnal influences on electrophysiological oscillations and coupling in the dorsal striatum and cerebellar cortex of the anesthetized rat. Frontiers in Systems Neuroscience, 8 (145). pp. 1-15. ISSN 1662-5137

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Official URL: http://dx.doi.org/10.3389/fnsys.2014.00145


Circadian rhythms modulate behavioral processes over a 24 h period through clock gene expression. What is largely unknown is how these molecular influences shape neural activity in different brain areas. The clock gene Per2 is rhythmically expressed in the striatum and the cerebellum and its expression is linked with daily fluctuations in extracellular dopamine levels and D2 receptor activity. Electrophysiologically, dopamine depletion enhances striatal local field potential (LFP) oscillations. We investigated if LFP oscillations and synchrony were influenced by time of day, potentially via dopamine mechanisms. To assess the presence of a diurnal effect, oscillatory power and coherence were examined in the striatum and cerebellum of rats under urethane anesthesia at four different times of day zeitgeber time (ZT1, 7, 13 and 19—indicating number of hours after lights turned on in a 12:12 h light-dark cycle). We also investigated the diurnal response to systemic raclopride, a D2 receptor antagonist. Time of day affected the proportion of LFP oscillations within the 0–3 Hz band and the 3–8 Hz band. In both the striatum and the cerebellum, slow oscillations were strongest at ZT1 and weakest at ZT13. A 3–8 Hz oscillation was present when the slow oscillation was lowest, with peak 3–8 Hz activity occurring at ZT13. Raclopride enhanced the slow oscillations, and had the greatest effect at ZT13. Within the striatum and with the cerebellum, 0–3 Hz coherence was greatest at ZT1, when the slow oscillations were strongest. Coherence was also affected the most by raclopride at ZT13. Our results suggest that neural oscillations in the cerebellum and striatum, and the synchrony between these areas, are modulated by time of day, and that these changes are influenced by dopamine manipulation. This may provide insight into how circadian gene transcription patterns influence network electrophysiology. Future experiments will address how these network alterations are linked with behavior.

Divisions:Concordia University > Research Units > Centre for Studies in Behavioural Neurobiology
Item Type:Article
Authors:Frederick, Ariana and Bourget-Murray, Jonathan and Chapman, C. Andrew and Amir, Shimon and Courtemanche, Richard
Journal or Publication:Frontiers in Systems Neuroscience
  • Natural Sciences and Engineering Research Council (NSERC) of Canada
  • CIHR
  • Concordia grant
  • Fonds de Recherche du Québec -Santé (FRQS
Digital Object Identifier (DOI):10.3389/fnsys.2014.00145
Keywords:local field potential oscillation, coherence, dopamine, circadian, urethane
ID Code:983751
Deposited By: MONIQUE LANE
Deposited On:16 Apr 2018 10:47
Last Modified:16 Apr 2018 10:47


Ahissar, E., Haidarliu, S., and Zacksenhouse, M. (1997). Decoding temporally encoded sensory input by cortical oscillations and thalamic phase comparators. Proc. Natl. Acad. Sci. U S A 94, 11633–11638. doi: 10.1073/pnas.94.21.11633

Albrecht, U., Bordon, A., Schmutz, I., and Ripperger, J. (2007). The multiple facets of Per2. Cold Spring Harb. Symp. Quant. Biol. 72, 95–104. doi: 10.1101/sqb.2007.72.001

Allen, G. I., and Tsukahara, N. (1974). Cerebrocerebellar communication systems. Physiol. Rev. 54, 957–1006.

Ballion, B., Frenois, F., Zold, C. L., Chetrit, J., Murer, M. G., and Gonon, F. (2009). D2 receptor stimulation, but not D1, restores striatal equilibrium in a rat model of Parkinsonism. Neurobiol. Dis. 35, 376–384. doi: 10.1016/j.nbd.2009.05.019

Başar, E., Başar-Eroglu, C., Karakaş, S., and Schürmann, M. (2001). Gamma, alpha, delta and theta oscillations govern cognitive processes. Int. J. Psychophysiol. 39, 241–248. doi: 10.1016/s0167-8760(00)00145-8

Berke, J. D., Okatan, M., Skurski, J., and Eichenbaum, H. B. (2004). Oscillatory entrainment of striatal neurons in freely moving rats. Neuron 43, 883–896. doi: 10.1016/j.neuron.2004.08.035

Bostan, A. C., Dum, R. P., and Strick, P. L. (2010). The basal ganglia communicate with the cerebellum. Proc. Natl. Acad. Sci. U S A 107, 8452–8456. doi: 10.1073/pnas.1000496107

Bostan, A. C., and Strick, P. L. (2010). The cerebellum and basal ganglia are interconnected. Neuropsychol. Rev. 20, 261–270. doi: 10.1007/s11065-010-9143-9

Bouthenet, M. L., Martres, M. P., Sales, N., and Schwartz, J. C. (1987). A detailed mapping of dopamine D-2 receptors in rat central nervous system by autoradiography with [125I]iodosulpride. Neuroscience 20, 117–155. doi: 10.1016/0306-4522(87)90008-x

Brown, P., Oliviero, A., Mazzone, P., Insola, A., Tonali, P., and Di Lazzaro, V. (2001). Dopamine dependency of oscillations between subthalamic nucleus and pallidum in Parkinson’s disease. J. Neurosci. 21, 1033–1038.

Bruguerolle, B., and Simon, N. (2002). Biologic rhythms and Parkinson’s disease: a chronopharmacologic approach to considering fluctuations in function. Clin. Neuropharmacol. 25, 194–201. doi: 10.1097/00002826-200207000-00002

Buehlmann, A., and Deco, G. (2010). Optimal information transfer in the cortex through synchronization. PLoS Comput. Biol. 6:e1000934. doi: 10.1371/journal.pcbi.1000934

Buzsáki, G. (2006). Rhythms of the Brain. New York: Oxford University Press.

Buzsáki, G., and Draguhn, A. (2004). Neuronal oscillations in cortical networks. Science 304, 1926–1929. doi: 10.1126/science.1099745

Buzsáki, G., and Moser, E. I. (2013). Memory, navigation and theta rhythm in the hippocampal-entorhinal system. Nat. Neurosci. 16, 130–138. doi: 10.1038/nn.3304

Calderon, D. P., Fremont, R., Kraenzlin, F., and Khodakhah, K. (2011). The neural substrates of rapid-onset Dystonia-Parkinsonism. Nat. Neurosci. 14, 357–365. doi: 10.1038/nn.2753

Chaudhury, D., Wang, L. M., and Colwell, C. S. (2005). Circadian regulation of hippocampal long-term potentiation. J. Biol. Rhythms 20, 225–236. doi: 10.1177/0748730405276352

Clement, E. A., Richard, A., Thwaites, M., Ailon, J., Peters, S., and Dickson, C. T. (2008). Cyclic and sleep-like spontaneous alternations of brain state under urethane anaesthesia. PLoS One 3:e2004. doi: 10.1371/journal.pone.0002004

Colwell, C. S. (2011). Linking neural activity and molecular oscillations in the SCN. Nat. Rev. Neurosci. 12, 553–569. doi: 10.1038/nrn3086

Costa, R. M., Lin, S. C., Sotnikova, T. D., Cyr, M., Gainetdinov, R. R., Caron, M. G., et al. (2006). Rapid alterations in corticostriatal ensemble coordination during acute dopamine-dependent motor dysfunction. Neuron 52, 359–369. doi: 10.1016/j.neuron.2006.07.030

Courtemanche, R., Chabaud, P., and Lamarre, Y. (2009). Synchronization in primate cerebellar granule cell layer local field potentials: basic anisotropy and dynamic changes during active expectancy. Front. Cell. Neurosci. 3:6. doi: 10.3389/neuro.03.006.2009

Courtemanche, R., Fujii, N., and Graybiel, A. M. (2003). Synchronous, focally modulated beta-band oscillations characterize local field potential activity in the striatum of awake behaving monkeys. J. Neurosci. 23, 11741–11752. doi: 10.3410/f.1002999.201447

Courtemanche, R., and Lamarre, Y. (2005). Local field potential oscillations in primate cerebellar cortex: synchronization with cerebral cortex during active and passive expectancy. J. Neurophysiol. 93, 2039–2052. doi: 10.1152/jn.00080.2004

Courtemanche, R., Pellerin, J. P., and Lamarre, Y. (2002). Local field potential oscillations in primate cerebellar cortex: modulation during active and passive expectancy. J. Neurophysiol. 88, 771–782. doi: 10.1152/jn.00718.2001

Courtemanche, R., Robinson, J. C., and Aponte, D. I. (2013). Linking oscillations in cerebellar circuits. Front. Neural Circuits 7:125. doi: 10.3389/fncir.2013.00125

Crittenden, J. R., and Graybiel, A. M. (2011). Basal ganglia disorders associated with imbalances in the striatal striosome and matrix compartments. Front. Neuroanat. 5:59. doi: 10.3389/fnana.2011.00059

Darna, M., Schmutz, I., Richter, K., Yelamanchili, S. V., Pendyala, G., Holtje, M., et al. (2009). Time of day-dependent sorting of the vesicular glutamate transporter to the plasma membrane. J. Biol. Chem. 284, 4300–4307. doi: 10.1074/jbc.m805480200

DeCoteau, W. E., Thorn, C., Gibson, D. J., Courtemanche, R., Mitra, P., Kubota, Y., et al. (2007a). Learning-related coordination of striatal and hippocampal theta rhythms during acquisition of a procedural maze task. Proc. Natl. Acad. Sci. U S A 104, 5644–5649. doi: 10.1073/pnas.0700818104

DeCoteau, W. E., Thorn, C., Gibson, D. J., Courtemanche, R., Mitra, P., Kubota, Y., et al. (2007b). Oscillations of local field potentials in the rat dorsal striatum during spontaneous and instructed behaviors. J. Neurophysiol. 97, 3800–3805. doi: 10.1152/jn.00108.2007

Dejean, C., Arbuthnott, G., Wickens, J. R., Le Moine, C., Boraud, T., and Hyland, B. I. (2011). Power fluctuations in beta and gamma frequencies in rat globus pallidus: association with specific phases of slow oscillations and differential modulation by dopamine D1 and D2 receptors. J. Neurosci. 31, 6098–6107. doi: 10.1523/JNEUROSCI.3311-09.2011

Delis, F., Mitsacos, A., and Giompres, P. (2004). Dopamine receptor and transporter levels are altered in the brain of Purkinje cell degeneration mutant mice. Neuroscience 125, 255–268. doi: 10.1016/j.neuroscience.2004.01.020

Destexhe, A., Contreras, D., and Steriade, M. (1999). Spatiotemporal analysis of local field potentials and unit discharges in cat cerebral cortex during natural wake and sleep states. J. Neurosci. 19, 4595–4608.

Doya, K. (2000). Complementary roles of basal ganglia and cerebellum in learning and motor control. Curr. Opin. Neurobiol. 10, 732–739. doi: 10.1016/s0959-4388(00)00153-7

Dugué, G. P., Brunel, N., Hakim, V., Schwartz, E. J., Chat, M., Lévesque, M., et al. (2009). Electrical coupling mediates tunable low-frequency oscillations and resonance in the cerebellar Golgi cell network. Neuron 61, 126–139. doi: 10.1016/j.neuron.2008.11.028

Ferris, M. J., Espana, R. A., Locke, J. L., Konstantopoulos, J. K., Rose, J. H., Chen, R., et al. (2014). Dopamine transporters govern diurnal variation in extracellular dopamine tone. Proc. Natl. Acad. Sci. U S A 111, E2751–E2759. doi: 10.1073/pnas.1407935111
Fowler, S. C., and Liou, J. R. (1998). Haloperidol, raclopride and eticlopride induce microcatalepsy during operant performance in rats, but clozapine and SCH 23390 do not. Psychopharmacology (Berl) 140, 81–90. doi: 10.1007/s002130050742

Frederick, A., Bourget-Murray, J., and Courtemanche, R. (2013). “Local field potential, synchrony of,” in Encyclopedia of Computational Neuroscience: Springer Reference, eds D. Jaeger and R. Jung (Berlin Heidelberg: Springer-Verlag). Available online at: http://www.springerreference.com

Giompres, P., and Delis, F. (2005). Dopamine transporters in the cerebellum of mutant mice. Cerebellum 4, 105–111. doi: 10.1080/14734220510007851

Grasing, K., and Szeto, H. (1992). Diurnal variation in continuous measures of the rat EEG power spectra. Physiol. Behav. 51, 249–254. doi: 10.1016/0031-9384(92)90138-r

Gravotta, L., Gavrila, A. M., Hood, S., and Amir, S. (2011). Global depletion of dopamine using intracerebroventricular 6-hydroxydopamine injection disrupts normal circadian wheel-running patterns and PERIOD2 expression in the rat forebrain. J. Mol. Neurosci. 45, 162–171. doi: 10.1007/s12031-011-9520-8

Graybiel, A. M. (2008). Habits, rituals and the evaluative brain. Annu. Rev. Neurosci. 31, 359–387. doi: 10.1146/annurev.neuro.29.051605.112851

Graybiel, A. M. (2010). “Templates for neural dynamics in the striatum: striosomes and matrisomes,” in Handbook of Brain Microcircuits, eds G. M. Shepherd and S. Grillner (New York, NY: Oxford University Press), 120–126.

Guilding, C., and Piggins, H. D. (2007). Challenging the omnipotence of the suprachiasmatic timekeeper: are circadian oscillators present throughout the mammalian brain? Eur. J. Neurosci. 25, 3195–3216. doi: 10.1111/j.1460-9568.2007.05581.x

Harbour, V. L., Weigl, Y., Robinson, B., and Amir, S. (2013). Comprehensive mapping of regional expression of the clock protein PERIOD2 in rat forebrain across the 24-h day. PLoS One 8:e76391. doi: 10.1371/journal.pone.0076391

Herrera-Meza, G., Aguirre-Manzo, L., Coria-Avila, G. A., Lopez-Meraz, M. L., Toledo-Cárdenas, R., Manzo, J., et al. (2014). Beyond the basal ganglia: cFOS expression in the cerebellum in response to acute and chronic dopaminergic alterations. Neuroscience 267, 219–231. doi: 10.1016/j.neuroscience.2014.02.046

Herzog, E. D. (2007). Neurons and networks in daily rhythms. Nat. Rev. Neurosci. 8, 790–802. doi: 10.1038/nrn2215
Hood, S., Cassidy, P., Cossette, M. P., Weigl, Y., Verwey, M., Robinson, B., et al. (2010). Endogenous dopamine regulates the rhythm of expression of the clock protein PER2 in the rat dorsal striatum via daily activation of D2 dopamine receptors. J. Neurosci. 30, 14046–14058. doi: 10.1523/JNEUROSCI.2128-10.2010

Hoshi, E., Tremblay, L., Feger, J., Carras, P. L., and Strick, P. L. (2005). The cerebellum communicates with the basal ganglia. Nat. Neurosci. 8, 1491–1493. doi: 10.1038/nn1544

Hurley, M. J., Mash, D. C., and Jenner, P. (2003). Markers for dopaminergic neurotransmission in the cerebellum in normal individuals and patients with Parkinson’s disease examined by RT-PCR. Eur. J. Neurosci. 18, 2668–2672. doi: 10.1046/j.1460-9568.2003.02963.x

Hutcheon, B., and Yarom, Y. (2000). Resonance, oscillation and the intrinsic frequency preferences of neurons. Trends Neurosci. 23, 216–222. doi: 10.1016/s0166-2236(00)01547-2

Ichinohe, N., Mori, F., and Shoumura, K. (2000). A di-synaptic projection from the lateral cerebellar nucleus to the laterodorsal part of the striatum via the central lateral nucleus of the thalamus in the rat. Brain Res. 880, 191–197. doi: 10.1016/s0006-8993(00)02744-x

Ikai, Y., Takada, M., Shinonaga, Y., and Mizuno, N. (1992). Dopaminergic and non-dopaminergic neurons in the ventral tegmental area of the rat project, respectively, to the cerebellar cortex and deep cerebellar nuclei. Neuroscience 51, 719–728. doi: 10.1016/0306-4522(92)90310-x

Imbesi, M., Yildiz, S., Dirim Arslan, A., Sharma, R., Manev, H., and Uz, T. (2009). Dopamine receptor-mediated regulation of neuronal “clock” gene expression. Neuroscience 158, 537–544. doi: 10.1016/j.neuroscience.2008.10.044

Ito, M. (2006). Cerebellar circuitry as a neuronal machine. Prog. Neurobiol. 78, 272–303. doi: 10.1016/j.pneurobio.2006.02.006

Kiss, B., Horti, F., and Bobok, A. (2011). In vitro and in vivo comparison of [3H](+)-PHNO and [3H]raclopride binding to rat striatum and lobes 9 and 10 of the cerebellum: a method to distinguish dopamine D(3) from D(2) receptor sites. Synapse 65, 467–478. doi: 10.1002/syn.20867

Koch, G., Brusa, L., Carrillo, F., Lo Gerfo, E., Torriero, S., Oliveri, M., et al. (2009). Cerebellar magnetic stimulation decreases levodopa-induced dyskinesias in Parkinson disease. Neurology 73, 113–119. doi: 10.1212/WNL.0b013e3181ad5387

Lemaire, N., Hernandez, L. F., Hu, D., Kubota, Y., Howe, M. W., and Graybiel, A. M. (2012). Effects of dopamine depletion on LFP oscillations in striatum are task- and learning-dependent and selectively reversed by L-DOPA. Proc. Natl. Acad. Sci. U S A 109, 18126–18131. doi: 10.1073/pnas.1216403109

Li, C. L., and Parker, L. O. (1969). Effect of dentate stimulation on neuronal activity in the globus pallidus. Exp. Neurol. 24, 298–309. doi: 10.1016/0014-4886(69)90023-5

Lim, C., and Allada, R. (2013). ATAXIN-2 activates PERIOD translation to sustain circadian rhythms in Drosophila. Science 340, 875–879. doi: 10.1126/science.1234785

Maggi, C. A., and Meli, A. (1986). Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 1: general considerations. Experientia 42, 109–114. doi: 10.1007/bf01952426

Magill, P. J., Sharott, A., Bolam, J. P., and Brown, P. (2004). Brain state-dependency of coherent oscillatory activity in the cerebral cortex and basal ganglia of the rat. J. Neurophysiol. 92, 2122–2136. doi: 10.1152/jn.00333.2004

Mallet, N., Le Moine, C., Charpier, S., and Gonon, F. (2005). Feedforward inhibition of projection neurons by fast-spiking GABA interneurons in the rat striatum in vivo. J. Neurosci. 25, 3857–3869. doi: 10.1523/jneurosci.5027-04.2005

Masubuchi, S., Honma, S., Abe, H., Ishizaki, K., Namihira, M., Ikeda, M., et al. (2000). Clock genes outside the suprachiasmatic nucleus involved in manifestation of locomotor activity rhythm in rats. Eur. J. Neurosci. 12, 4206–4214. doi: 10.1111/j.1460-9568.2000.01313.x

Mayne, E. W., Craig, M. T., McBain, C. J., and Paulsen, O. (2013). Dopamine suppresses persistent network activity via D(1) -like dopamine receptors in rat medial entorhinal cortex. Eur. J. Neurosci. 37, 1242–1247. doi: 10.1111/ejn.12125

McCormick, D. A. (2004). “Membrane properties and neurotransmitter actions,” in The Synaptic Organization of the Brain, ed G. M. Shepherd (New York, NY: Oxford University Press), 39–77.

Mendoza, J., Pevet, P., Felder-Schmittbuhl, M. P., Bailly, Y., and Challet, E. (2010). The cerebellum harbors a circadian oscillator involved in food anticipation. J. Neurosci. 30, 1894–1904. doi: 10.1523/JNEUROSCI.5855-09.2010

Middleton, F. A., and Strick, P. L. (2000). Basal ganglia and cerebellar loops: motor and cognitive circuits. Brain Res. Brain Res. Rev. 31, 236–250. doi: 10.1016/s0165-0173(99)00040-5

Moers-Hornikx, V. M., Vles, J. S., Tan, S. K., Cox, K., Hoogland, G., Steinbusch, W. M., et al. (2011). Cerebellar nuclei are activated by high-frequency stimulation of the subthalamic nucleus. Neurosci. Lett. 496, 111–115. doi: 10.1016/j.neulet.2011.03.094

Monti, J. M., and Monti, D. (2007). The involvement of dopamine in the modulation of sleep and waking. Sleep Med. Rev. 11, 113–133. doi: 10.1016/j.smrv.2006.08.003

Mordel, J., Karnas, D., Pevet, P., Isope, P., Challet, E., and Meissl, H. (2013). The output signal of Purkinje cells of the cerebellum and circadian rhythmicity. PLoS One 8:e58457. doi: 10.1371/journal.pone.0058457

Morissette, J., and Bower, J. M. (1996). Contribution of somatosensory cortex to responses in the rat cerebellar granule cell layer following peripheral tactile stimulation. Exp. Brain Res. 109, 240–250. doi: 10.1007/bf00231784

Namihira, M., Honma, S., Abe, H., Tanahashi, Y., Ikeda, M., and Honma, K. (1999). Daily variation and light responsiveness of mammalian clock gene, Clock and BMAL1, transcripts in the pineal body and different areas of brain in rats. Neurosci. Lett. 267, 69–72. doi: 10.1016/s0304-3940(99)00324-9

Nicolelis, M. A. L., Baccala, L. A., Lin, R. C. S., and Chapin, J. K. (1995). Sensorimotor encoding by synchronous neural ensemble activity at multiple levels of the somatosensory system. Science 268, 1353–1358. doi: 10.1126/science.7761855

Nutt, J. G., Carter, J. H., Lea, E. S., and Woodward, W. R. (1997). Motor fluctuations during continuous levodopa infusions in patients with Parkinson’s disease. Mov. Disord. 12, 285–292. doi: 10.1002/mds.870120304

Owasoyo, J. O., Walker, C. A., and Whitworth, U. G. (1979). Diurnal variation in the dopamine level of rat brain areas: effect of sodium phenobarbital. Life Sci. 25, 119–122. doi: 10.1016/0024-3205(79)90382-5

Paxinos, G., and Watson, C. (1998). The Rat Brain in Stereotaxic Coordinates. SanDiego, CA: Academic Press.

Pellerin, J. P., and Lamarre, Y. (1997). Local field potential oscillations in primate cerebellar cortex during voluntary movement. J. Neurophysiol. 78, 3502–3507.

Ratcheson, R. A., and Li, C. L. (1969). Effect of dentate stimulation on neuronal activity in the caudate nucleus. Exp. Neurol. 25, 268–281. doi: 10.1016/0014-4886(69)90050-8

Rath, M. F., Rohde, K., and Moller, M. (2012). Circadian oscillations of molecular clock components in the cerebellar cortex of the rat. Chronobiol. Int. 29, 1289–1299. doi: 10.3109/07420528.2012.728660

Rivlin-Etzion, M., Marmor, O., Heimer, G., Raz, A., Nini, A., and Bergman, H. (2006). Basal ganglia oscillations and pathophysiology of movement disorders. Curr. Opin. Neurobiol. 16, 629–637. doi: 10.1016/j.conb.2006.10.002

Roopun, A. K., Lebeau, F. E., Rammell, J., Cunningham, M. O., Traub, R. D., and Whittington, M. A. (2010). Cholinergic neuromodulation controls directed temporal communication in neocortex in vitro. Front. Neural Circuits 4:8. doi: 10.3389/fncir.2010.00008

Ros, H., Sachdev, R. N., Yu, Y., Sestan, N., and McCormick, D. A. (2009). Neocortical networks entrain neuronal circuits in cerebellar cortex. J. Neurosci. 29, 10309–10320. doi: 10.1523/JNEUROSCI.2327-09.2009

Sanchez-Vives, M. V., and McCormick, D. A. (2000). Cellular and network mechanisms of rhythmic recurrent activity in neocortex. Nat. Neurosci. 3, 1027–1034. doi: 10.1038/79848

Schnitzler, A., and Gross, J. (2005). Normal and pathological oscillatory communication in the brain. Nat. Rev. Neurosci. 6, 285–296. doi: 10.1038/nrn1650

Schweighofer, N., Doya, K., and Kuroda, S. (2004). Cerebellar aminergic neuromodulation: towards a functional understanding. Brain Res. Brain Res. Rev. 44, 103–116. doi: 10.1016/j.brainresrev.2003.10.004

Sharma, A. V., Wolansky, T., and Dickson, C. T. (2010). A comparison of sleeplike slow oscillations in the hippocampus under ketamine and urethane anesthesia. J. Neurophysiol. 104, 932–939. doi: 10.1152/jn.01065.2009

Sharott, A., Doig, N. M., Mallet, N., and Magill, P. J. (2012). Relationships between the firing of identified striatal interneurons and spontaneous and driven cortical activities in vivo. J. Neurosci. 32, 13221–13236. doi: 10.1523/jneurosci.2440-12.2012

Sharott, A., Magill, P. J., Harnack, D., Kupsch, A., Meissner, W., and Brown, P. (2005). Dopamine depletion increases the power and coherence of beta-oscillations in the cerebral cortex and subthalamic nucleus of the awake rat. Eur. J. Neurosci. 21, 1413–1422. doi: 10.1111/j.1460-9568.2005.03973.x

Shieh, K. R. (2003). Distribution of the rhythm-related genes rPERIOD1, rPERIOD2 and rCLOCK, in the rat brain. Neuroscience 118, 831–843. doi: 10.1016/s0306-4522(03)00004-6

Steriade, M. (2003). Neuronal Substrates of Sleep and Epilepsy. Cambridge, UK: Cambridge University Press.

Stern, E. A., Jaeger, D., and Wilson, C. J. (1998). Membrane potential synchrony of simultaneously recorded striatal spiny neurons in vivo. Nature 394, 475–478. doi: 10.1038/28848

Takada, M., Sugimoto, T., and Hattori, T. (1993). MPTP neurotoxicity to cerebellar Purkinje cells in mice. Neurosci. Lett. 150, 49–52. doi: 10.1016/0304-3940(93)90105-t

Thorn, C. A., Atallah, H., Howe, M., and Graybiel, A. M. (2010). Differential dynamics of activity changes in dorsolateral and dorsomedial striatal loops during learning. Neuron 66, 781–795. doi: 10.1016/j.neuron.2010.04.036

Thorn, C. A., and Graybiel, A. M. (2014). Differential entrainment and learning-related dynamics of spike and local field potential activity in the sensorimotor and associative striatum. J. Neurosci. 34, 2845–2859. doi: 10.1523/jneurosci.1782-13.2014

Tseng, K. Y., Kasanetz, F., Kargieman, L., Riquelme, L. A., and Murer, M. G. (2001). Cortical slow oscillatory activity is reflected in the membrane potential and spike trains of striatal neurons in rats with chronic nigrostriatal lesions. J. Neurosci. 21, 6430–6439.

Uhlhaas, P. J., Roux, F., Rodriguez, E., Rotarska-Jagiela, A., and Singer, W. (2010). Neural synchrony and the development of cortical networks. Trends Cogn. Sci. 14, 72–80. doi: 10.1016/j.tics.2009.12.002

Valencia, M., Artieda, J., Bolam, J. P., and Mena-Segovia, J. (2013). Dynamic interaction of spindles and gamma activity during cortical slow oscillations and its modulation by subcortical afferents. PLoS One 8:e67540. doi: 10.1371/journal.pone.0067540

Verwey, M., and Amir, S. (2012). Variable restricted feeding disrupts the daily oscillations of Period2 expression in the limbic forebrain and dorsal striatum in rats. J. Mol. Neurosci. 46, 258–264. doi: 10.1007/s12031-011ds-9529-z

Walters, J. R., Hu, D., Itoga, C. A., Parr-Brownlie, L. C., and Bergstrom, D. A. (2007). Phase relationships support a role for coordinated activity in the indirect pathway in organizing slow oscillations in basal ganglia output after loss of dopamine. Neuroscience 144, 762–776. doi: 10.1016/j.neuroscience.2006.10.006

Watson, T. C., Becker, N., Apps, R., and Jones, M. W. (2014). Back to front: cerebellar connections and interactions with the prefrontal cortex. Front. Syst. Neurosci. 8:4. doi: 10.3389/fnsys.2014.00004

Wilder-Smith, E., Tan, E. K., Law, H. Y., Zhao, Y., Ng, I., and Wong, M. C. (2003). Spinocerebellar ataxia type 3 presenting as an L-DOPA responsive dystonia phenotype in a Chinese family. J. Neurol. Sci. 213, 25–28. doi: 10.1016/s0022-510x(03)00129-1

Wilson, C. J., and Kawaguchi, Y. (1996). The origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons. J. Neurosci. 16, 2397–2410.

Zeitzer, J. M. (2013). Control of sleep and wakefulness in health and disease. Prog. Mol. Biol. Transl. Sci. 119, 137–154. doi: 10.1016/B978-0-12-396971-2.00006-3

Zhang, Y., Ling, J., Yuan, C., Dubruille, R., and Emery, P. (2013). A role for Drosophila ATX2 in activation of PER translation and circadian behavior. Science 340, 879–882. doi: 10.1126/science.1234746
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