Abstract

This thesis presents the design of a relational database supporting high-throughput assays to determine enzyme catalytic activity--The Enzyme Activity Mapping Database ( EAMDB ). The database is composed of six modules: enzyme module, chemical compound module, enzyme activity mapping module, experiment module, data module, and reference module. Each module has one or more tables to cover relevant information. There are 17 tables in the database. Primary key and foreign key constraints have been introduced to enforce data integrity. The database can be integrated into a bioinformatics database system to provide enzyme function information to serve scientists for their various research interests.